76: Hypothyroidism — Diagnosis, Treatment, and Medication with Dr. Leonard Wartofsky from MedStar

Dr. Wartofsky is Professor of Medicine, Georgetown University School of Medicine and Chairman Emeritus, Department of Medicine, MedStar Washington Hospital Center.  He trained in internal medicine at Barnes Hospital, Washington University and in endocrinology with Dr. Sidney Ingbar, Harvard University Service, Thorndike Memorial Laboratory, Boston.   In this episode, Dr. Wartofsky discusses the following: * Hypothyroidism causes * When is replacement thyroid replacement hormone necessary? * The history of replacement thyroid hormone going back to 1891 * The early treatment included a chopped up sheep thyroid and served as a 'tartar', often resulting in vomiting * Myxedema coma

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75: Thyroid Cancer Does Not Respond to RAI⎢Treatment Options

In this episode, topics include: * Drug therapy for patients that fail standard therapy; including surgery and RAI * Not all patients have same behavior for their cancer * Some cancers are aggressive * Not many thyroid cancer patients are affected by this; maybe a few thousand in the U.S., but not tens of thousands * What is the treatment protocol for therapy? * Lenvatinib or Sorafenib is the treatment for refectory thyroid cancer * Lenvatinib tends to be more effective * Sorafenib is tolerated by the patient better * Other options to consider include, molecular profiling or some thyroid cancers carry mutation that is targetable, or BRAF * BRAF inhibitors used with thyroid cancer patients * Molecular profiling * DNA sequencing

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74: Thyroid and Pregnancy⎥Why It Matters, with Dr. Elizabeth Pearce from Boston University

In this episode, topics include: * Hypothyroidism and hyperthyroidism during pregnancy * Pregnant and without a thyroid * Avoiding T3 during pregnancy, including concerns with desiccated thyroid * If being treated for hypothyroidism already, the importance of upping dose while pregnant * Pregnant with auto-immunity * Pregnant with Graves' disease * The dangers of pregnancy and overt hypothyroidism or hyperthyroidism

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73: Innovaciones en el Tratamiento del Cáncer de Tiroides, con el Dr. Hernán Tala desde Santiago, Chile

Dr. Hernán Tala es endocrinólogo de la Clinica Alemana en Santiago, Chile. Su area especialidad incluye cáncer de tiroides avanzado, endocrinologia general, y enfermedades tiroides. Los temas presentados incluyen: * Una mejor comprensión de la biología del cáncer de tiroides, y que no todo el cáncer de tiroides es igual. La enfermedad es única en cada paciente. * La importancia de entender el perfil del cáncer en cada paciente. * Diagnóstico del nódulo. * Perfil molecular del nódulo tiroideo. * Una pausa en la exploración universal del cáncer de tiroides. * Vigilancia activa

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71: Hipotiroidismo – Causas, Síntomas, y Exámenes. Con la Dra. Gabriela Brenta de Buenos Aires

Hipotiroidismo: el tratamiento, pronóstico, posibles complicaciones, y cuándo contactar a un médico. La tiroides produce hormonas que controlan la forma como cada célula en el cuerpo usa la energía. Este proceso se denomina metabolismo. Hipotiroidismo es una afección en la cual la glándula tiroides no produce suficiente hormona tiroidea. Esta afección a menudo se llama tiroides hipoactiva.

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70: Cáncer de Tiroides, con la Dra Ines Califano de Universidad de Buenos Aires

Cáncer de Tiroides, con la Dra Ines Califano de Universidad de Buenos Aires Reduzca la ansiedad durante el tratamiento del cáncer de tiroides En esta entrevista, discutimos lo siguiente: 1. ¿Qué es un nódulo? 2. ¿Qué sucede durante ecografia? 3. ¿Qué sucede durante la oja fina? 4. Si es cáncer, ¿siempre hace la cirugía? 5. Si no es cáncer, ¿algunas veces hace cirugía?

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67: Molecular Profiling and Unnecessary Thyroid Surgeries with Jennifer Kuo from Columbia University

One-third of all thyroid nodule fine needle aspirations come back indeterminate. When surgery is performed on these cases, pathology of the thyroid reveals that many times the nodule is benign.  Through molecular profiling, patients with indeterminate thyroid nodules, can now avoid unnecessary surgery and get more accurate pathology results from the fine needle aspiration. Are you a patient and your doctor has said your thyroid nodule is indeterminate and is recommending surgery as an option?  The key is, to confirm that molecular profiling was performed.    Jennifer Kuo, MD is Director of the Thyroid Biopsy Program, Director of the Endocrine Surgery Research Program, and Instructor in Surgery, at the Columbia University Medical Center. 

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66: New Research Reveals Thyroid Surgery Errors 5x More Frequent Than Reported with Dr. Maria Papaleontiou from Michigan Medicine

Scheduled to publish next month, the statistics show thyroid surgery much less safe than thought. The findings that 12% of patients overall had thyroid surgery specific complications is concerning, but more concerning is surgeons quote a 1 to 3 percent rate of error. In the case of surgery for metastatic thyroid cancer, the error rate skyrockets to 23%. Dr. Maria Papaleontiou is an Assistant Professor of Internal Medicine with an appointment in the Division of Metabolism, Endocrinology and Diabetes.

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