50: Regarding Thyroid Cancer, Are You a Minimalist or a Maximalist? with Dr. Michael Tuttle from Sloan Kettering


Regarding Thyroid Cancer, Are You a Minimalist or a Maximalist?
Often, surgery is not necessary to treat thyroid cancer, but much of the decision will depend on the patient characteristic.
During this interview, Dr. Tuttle discusses the following points:
Challenges of managing thyroid cancer as outlined by the guidelines
Scaling back care for insurance-challenged patients, and adopting a plan that gets the same result without needing the expensive tests
Desired outcome is survival and no recurrence, a third is for no harm that would be caused by an unnecessary surgery
Unwanted side affects of thyroid cancer include nerve damage, parathyroid damage, and infections

49: Thyroid and Pregnancy⎥Why It Matters, with Dr. Elizabeth Pearce from Boston University


In this episode, topics include:
* Hypothyroidism and hyperthyroidism during pregnancy
* Pregnant and without a thyroid
* Avoiding T3 during pregnancy, including concerns with desiccated thyroid
* If being treated for hypothyroidism already, the importance of upping dose while pregnant
* Pregnant with auto-immunity
* Pregnant with Graves’ disease
* The dangers of pregnancy and overt hypothyroidism or hyperthyroidism

48: Innovaciones en el Tratamiento del Cáncer de Tiroides, con el Dr. Hernán Tala desde Santiago, Chile


Dr. Hernán Tala es endocrinólogo de la Clinica Alemana en Santiago, Chile. Su area especialidad incluye cáncer de tiroides avanzado, endocrinologia general, y enfermedades tiroides.
Los temas presentados incluyen:
* Una mejor comprensión de la biología del cáncer de tiroides, y que no todo el cáncer de tiroides es igual. La enfermedad es única en cada paciente.
* La importancia de entender el perfil del cáncer en cada paciente.
* Diagnóstico del nódulo.
* Perfil molecular del nódulo tiroideo.
* Una pausa en la exploración universal del cáncer de tiroides.
* Vigilancia activa

47: Treatment of Thyroid Cancer in Japan, with Dr. Takahiro Okamoto from Tokyo Women’s Medical University

A different approach to treating thyroid cancer compared to the U.S.

Dr. Takahiro Okamoto helped write the Japanese guidelines on thyroid cancer.  He is Professor & Chair of the Department of Surgery at Tokyo Women’s Medical University. 
Key points from this episode include:
* Most Western countries carry out total thyroidectomies, whereas in Japan, the approach is more conservative with a fundamental practice of hemithyroidectomy whenever possible.
* By not doing a total thyroidectomy, this allows the patient to not avoid taking thyroid replacement medication.
* Complete thyroidectomy is conducted when 80-90% of lymph nodes have metastasis.
* I-131 treatment is decreasing despite cases of cancer increasing
* For I-131 treatment, patients wait more than 6 months post surgery.
* When receving I-131 treatment, patients be admitted to hospital for several days.
* TSH suppression therapy is common in Western countries, whereas in Japan, measures are taken to avoid TSH suppression by not removing all of the thyroid.
* Normal TSH in Japan is 4.3 or less.

46: Nerve Monitoring During Thyroid Surgery, with Dr. Özer Makay from Ege University – Turkey

Dr. Özer Makay is an expert in nerve monitoring during thyroid surgery, and has been a guest faculty member in South Korea, Italy, France, the Netherlands, Germany, Belgium and Bulgaria. 

This episode covers the following topics:
* Protecting the recurrent laryngeal nerve (RLN) and superior laryngeal nerve during thyroid surgery.
* Outcomes of damaging these nerves during surgery include no voice, hoarseness, shortness of breath, problem with drinking water or aspiration, impaired physical exertion with something as simple as climbing a flight of stairs.
* Why some centers have a higher occurrence of damage during thyroid surgery and include an error rate as high as 10%
* The cause of the damaged nerve include stretching or traction, and cutting or stitching.
* How to reduce risk.
* Is it possible to reattach a cut nerve?

45: Hipotiroidismo – Causas, Síntomas, y Exámenes. Con la Dra. Gabriela Brenta de Buenos Aires

Hipotiroidismo: el tratamiento, pronóstico, posibles complicaciones, y cuándo contactar a un médico.
La tiroides produce hormonas que controlan la forma como cada célula en el cuerpo usa la energía. Este proceso se denomina metabolismo.
Hipotiroidismo es una afección en la cual la glándula tiroides no produce suficiente hormona tiroidea. Esta afección a menudo se llama tiroides hipoactiva.

44: Cáncer de Tiroides, con la Dra Ines Califano de Universidad de Buenos Aires


Cáncer de Tiroides, con la Dra Ines Califano de Universidad de Buenos Aires
Reduzca la ansiedad durante el tratamiento del cáncer de tiroides
En esta entrevista, discutimos lo siguiente:
1. ¿Qué es un nódulo?
2. ¿Qué sucede durante ecografia?
3. ¿Qué sucede durante la oja fina?
4. Si es cáncer, ¿siempre hace la cirugía?
5. Si no es cáncer, ¿algunas veces hace cirugía?

43: A Summary of Radioactive Iodine Treatment for Thyroid Cancer, with Dr. Alan Waxman from Cedars Sinai


Not all thyroid cancer patients who receive a thyroidectomy require radioactive iodine, but for those whose cancer maybe more aggressive and spread beyond the thyroid area, often radioactive iodine (RAI) is protocol.
RAI treatment may vary depending on the hospital.
In this interview, Dr. Alan Waxman explains what occurs leading up to, during, and after RAI. Topics discussed include:
If staying at the hospital after taking RAI, how long is the stay required?
Should you go home after RAI?
What is the benefit of staying overnight at the hospital when receiving RAI?
Worldwide trends toward prescribing lower doses of RAI.
Is there risk in RAI causing leukemia?

42: Flame Retardants Connected to Thyroid Cancer, with Dr. Julie Ann Sosa from Duke University


This is an in depth discussion about the connection between flame retardants and plastics, and thyroid cancer.  These chemicals, also known as endocrine disruptors, have a clear connection to thyroid cancer occurrence.
The research is presented by Julie Ann Sosa, MD MA FACS is Chief of Endocrine Surgery at Duke University and leader of the endocrine neoplasia diseases group in the Duke Cancer Institute and the Duke Clinical Research Institute. She is Professor of Surgery and Medicine. Her clinical interest is in endocrine surgery, with a focus in thyroid cancer. 

41: Molecular Profiling and Unnecessary Thyroid Surgeries with Jennifer Kuo from Columbia University


One-third of all thyroid nodule fine needle aspirations come back indeterminate. When surgery is performed on these cases, pathology of the thyroid reveals that many times the nodule is benign.  Through molecular profiling, patients with indeterminate thyroid nodules, can now avoid unnecessary surgery and get more accurate pathology results from the fine needle aspiration.
Are you a patient and your doctor has said your thyroid nodule is indeterminate and is recommending surgery as an option?  The key is, to confirm that molecular profiling was performed.   
Jennifer Kuo, MD is Director of the Thyroid Biopsy Program, Director of the Endocrine Surgery Research Program, and Instructor in Surgery, at the Columbia University Medical Center.